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It was suggested that the strong anti-neuroinflammatory activity of the fresh ginger extract was largely contributed by 10-gingerol ( In addition, 6-, 8- and 10-gingerols/shogaols were shown to inhibit the canonical (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-mediated IL-1 secretion in ATP- and LPS-stimulated THP-1 macrophages

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In line with the IR-senescence data, low effective doses of FOXO4-DRI were well tolerated in normal IMR90 compared to ABT-737 while being very potent against doxorubicin-senescent cells at higher doses

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For example: A rat experiment reported that ipamorelin therapy significantly increased bone mineral content after 12 weeks compared to placebo, as measured by DEXA (dual-energy X-ray absorptiometry) [21]